Now showing items 1-12 of 12

    • Villamizar Sarmiento, María Gabriela; Molina-Soto, Elton F.; Guerrero, Juan; Shibue, Toshimichi; Nishide, Hiroyuki; Moreno Villoslada, Ignacio; Oyarzún Ampuero, Felipe (American Chemical Society, 2019)
      To date, a large number of active molecules are hydrophilic and aromatic low molecular-weight drugs (HALMD). Unfortunately, the low capacity of these molecules to interact with excipients and the fast release when a ...
    • Vidal, Alejandra; Mendieta Zerón, Hugo; Giacaman, Israel; Camarillo Romero, María del Socorro; Parra López, Sandra; Meza Trillo, Laura E.; Pérez Pérez, David A.; Concha, Miguel; Torres Gallegos, César; Orellana, Sandra L.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2015)
      The incidence of ulcers associated to type 2 diabetes mellitus (T2DM) increases every year. We introduce and explore a new mathematical algorithm to evaluate wound-healing in foot ulcers associated to T2DM. Fifteen patients ...
    • Pino Pinto, Juan Pablo; Oyarzún Ampuero, Felipe; Orellana, Sandra L.; Flores, Mario E.; Nishide, Hiroyuki; Moreno Villoslada, Ignacio (Elsevier, 2017)
      Aerogels made of chitosan and chondroitin sulfate, and containing 5,10,15,20-tetrakis-(4- sulfonatophenyl)-porphyrin have been synthesized. The aerogels presented a microstructure made of microfibers and microsheets, ...
    • Orellana, Sandra L.; Torres Gallegos, César; Araya Hermosilla, Rodrigo; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (John Wiley, 2015)
      The association efficiency of oxytetracycline (OTC) to pharmaceutical available, ionic oil-in-water nanoemulsions is studied. Theoretical mathematical developments allowed us to differentiate by diafiltration (DF) between ...
    • Gómez Tardajos, Myriam; Pino Pinto, Juan Pablo; Díaz Soto, Claudia; Flores, Mario E.; Gallardo, Alberto; Elvira, Carlos; Reinecke, Helmut; Nishide, Hiroyuki; Moreno Villoslada, Ignacio (Elsevier, 2013)
      Polymeric derivatives of the biocompatible poly(vinylpyrrolidone) bearing discrete amounts of aromatic amines have been synthesized. The interaction of 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin with a series of ...
    • Villamizar Sarmiento, María Gabriela (Universidad de Chile, 2020)
      La administración de fármacos hidrofílicos de bajo peso molecular constituye un gran desafío en drug delivery, sobre todo para la terapia de enfermedades crónicas. La biodistribución parcial y rápida eliminación de estas ...
    • Flores Flores, Mario Enrique (Universidad de Chile, 2015)
      El trabajo a continuación explora el proceso de asociación de moléculas anfifílicas no iónicas en solventes apolares y el efecto ligante del agua en este proceso de asociación. En específico, se han estudiado tres moléculas ...
    • Araya Hermosilla, Esteban; Muñoz, Daniel; Orellana, Sandra; Yáñez, Alejandro; Olea, Andrés F.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2014)
      Immobilization of rhodamine 6G in calcium alginate microcapsules was achieved using the polyanion bearing negatively charged aromatic groups poly(sodium 4-styrenesulfonate) as complexing agent. The immobilization of the ...
    • Araya Hermosilla, Esteban; Muñoz, Daniel; Orellana, Sandra; Yáñez, Alejandro; Olea, Andrés F.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2014)
      Immobilization of rhodamine 6G in calcium alginate microcapsules was achieved using the polyanion bearing negatively charged aromatic groups poly(sodium 4-styrenesulfonate) as complexing agent. The immobilization of the ...
    • Oyarzún Ampuero, Felipe; Vidal, Alejandra; Concha, Miguel; Morales Montecinos, Javier; Orellana, Sandra; Moreno Villoslada, Ignacio (Bentham, 2015)
      The treatment of skin wounds represents an important research area due to the important physiological and aesthetic role of this tissue. During the last years, nanoparticles have emerged as important platforms to treat ...
    • Sanhueza, Luis; Castro, Joaquín; Urzúa, Esteban; Barrientos, Lorena; Oyarzún Ampuero, Felipe; Pesenti, Héctor; Shibue, Toshimichi; Sugimura, Natsuhiko; Tomita, Wataru; Nishide, Hiroyuki; Moreno Villoslada, Ignacio (American Chemical Society, 2015)
      Photochromic solid materials based on the cationic polymer poly(decylviologen) are reported. The solids were obtained by freeze-drying colloidal suspensions of nanocomplexes obtained by mixing aqueous solutions of the ...
    • Flores, Mario E.; Martínez Díaz, Francisco; Olea, Andrés F.; Shibue, Toshimichi; Sugimura, Natsuhiko; Nishide, Hiroyuki; Moreno Villoslada, Ignacio (American Chemical Society, 2015)
      The formation of emulsions upon reverse self-association of the monodisperse amphiphilic block copolymer poly(ethylene oxide)(43)-b-poly(epsilon-caprolactone)(14) in cydohexanone is reported. Such emulsions are not formed ...